TY - JOUR
T1 - Potential Applications of Cucurbit[n]urils Inclusion Complexes in Photodynamic Therapy
AU - Robinson-Duggon, José
AU - Pérez-Mora, Francisco
AU - Dibona-Villanueva, Luciano
AU - Fuentealba, Denis
N1 - Publisher Copyright:
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2018/4
Y1 - 2018/4
N2 - Cucurbit[n]urils (CB[n]s) have emerged as potential candidates for drug delivery in several areas due to their strong binding interactions and low toxicity. More recently, their benefits for a type of cancer treatment termed Photodynamic Therapy (PDT) have been recognized. The outcomes of this therapy rely on better drug delivery strategies and improving overall photoactivity of the drugs, which is where CB[n]s could have a strong impact. The effects of these molecular containers on photoactivity are discussed and new interesting work is highlighted.
AB - Cucurbit[n]urils (CB[n]s) have emerged as potential candidates for drug delivery in several areas due to their strong binding interactions and low toxicity. More recently, their benefits for a type of cancer treatment termed Photodynamic Therapy (PDT) have been recognized. The outcomes of this therapy rely on better drug delivery strategies and improving overall photoactivity of the drugs, which is where CB[n]s could have a strong impact. The effects of these molecular containers on photoactivity are discussed and new interesting work is highlighted.
KW - cucurbit[n]uril
KW - inclusion complex
KW - Photodynamic therapy
KW - photosensitizer
KW - singlet oxygen
UR - http://www.scopus.com/inward/record.url?scp=85032977428&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000430466900003&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1002/ijch.201700093
DO - 10.1002/ijch.201700093
M3 - Review
AN - SCOPUS:85032977428
SN - 0021-2148
VL - 58
SP - 199
EP - 214
JO - Israel Journal of Chemistry
JF - Israel Journal of Chemistry
IS - 3
ER -