Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas

Ofir Arad, Ana Gavaldá, Óscar Rey, Noemi Rubio, David Sánchez-García, José I. Borrell, Jordi Teixidó, Santiago Nonell, Magdalena Cañete, Angeles Juarranz, Angeles Villanueva, Juan C. Stockert, Pablo J. Díaz Jiménez

Producció científica: Article en revista indexadaArticleAvaluat per experts

9 Cites (Scopus)

Resum

The photodynamic therapy (PDT) or photochemotherapy of cancer is a treatment modality that uses a photosensitizing drug with tumor-localizing properties. Irradiation of the tumor cells with light results in the formation of highly reactive, cytotoxic oxygen species that induce the death of malignant cells. The development of new photosensitizers for localization and treatment of tumors is a research area or current interest, parallelled by the development of novel non-oncological applications of these drugs. Our group is focused on the study and development of porphycenes, structural isomers of porphyrins, with better photochemical and photosensitizing properties. Porphycenes are highly attractive candidates to be used as photosensitizers for PDT and other biomedical applications.

Títol traduït de la contribucióPorphycene for cancer photochemotherapy and other biomedical applications
Idioma originalCastellà
Pàgines (de-a)343-356
Nombre de pàgines14
RevistaAfinidad
Volum59
Número500
Estat de la publicacióPublicada - de jul. 2002

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