Personalized nanomedicine: A revolution at the nanoscale

Cristina Fornaguera, Maria José García-Celma

Producció científica: Article en revista indexadaArticle de revisió (sistemàtica)Avaluat per experts

104 Cites (Scopus)

Resum

Nanomedicine is an interdisciplinary research field that results from the application of nanotechnology to medicine and has the potential to significantly improve some current treatments Specifically, in the field of personalized medicine, it is expected to have a great impact in the near future due to its multiple advantages, namely its versatility to adapt a drug to a cohort of patients. In the present review, the properties and requirements of pharmaceutical dosage forms at the nanoscale, so-called nanomedicines, are been highlighted. An overview of the main current nanomedicines in pre-clinical and clinical development is presented, detailing the challenges to the personalization of these therapies. Next, the process of development of novel nanomedicines is described, from their design in research labs to their arrival on the market, including considerations for the design of nanomedicines adapted to the requirements of the market to achieve safe, effective, and quality products. Finally, attention is given to the point of view of the pharmaceutical industry including regulation issues applied to the specific case of personalized medicine. The authors expect this review to be a useful overview of the current state of the art of nanomedicine research and industrial production, and the future opportunities of personalized medicine in the upcoming years The authors encourage the development and marketing of novel personalized nanomedicines.

Idioma originalAnglès
Número d’article12
RevistaJournal of Personalized Medicine
Volum7
Número4
DOIs
Estat de la publicacióPublicada - de des. 2017
Publicat externament

Fingerprint

Navegar pels temes de recerca de 'Personalized nanomedicine: A revolution at the nanoscale'. Junts formen un fingerprint únic.

Com citar-ho