TY - JOUR
T1 - Non-linear Functional Brain Co-activations in Short-Term Memory Distortion Tasks
AU - Ceglarek, Anna
AU - Ochab, Jeremi K.
AU - Cifre, Ignacio
AU - Fafrowicz, Magdalena
AU - Sikora-Wachowicz, Barbara
AU - Lewandowska, Koryna
AU - Bohaterewicz, Bartosz
AU - Marek, Tadeusz
AU - Chialvo, Dante R.
N1 - Funding Information:
This study was funded by the Polish National Science Centre through grants: Harmonia 2013/08/M/HS6/00042 (MF), Sonata 2015/17/D/ST2/03492 (JO), and supported by the Foundation for Polish Science (FNP) project “Bio-inspired Artificial Neural Networks” (POIR.04.04.00-00-14DE/18-00). The open access license of the publication was funded by the Priority Research Area Society of the Future under the program “Excellence Initiative – Research University” at the Jagiellonian University in Kraków.
Publisher Copyright:
Copyright © 2021 Ceglarek, Ochab, Cifre, Fafrowicz, Sikora-Wachowicz, Lewandowska, Bohaterewicz, Marek and Chialvo.
PY - 2021/12/3
Y1 - 2021/12/3
N2 - Recent works shed light on the neural correlates of true and false recognition and the influence of time of day on cognitive performance. The current study aimed to investigate the modulation of the false memory formation by the time of day using a non-linear correlation analysis originally designed for fMRI resting-state data. Fifty-four young and healthy participants (32 females, mean age: 24.17 ± 3.56 y.o.) performed in MR scanner the modified Deese-Roediger-McDermott paradigm in short-term memory during one session in the morning and another in the evening. Subjects’ responses were modeled with a general linear model, which includes as a predictor the non-linear correlations of regional BOLD activity with the stimuli, separately for encoding and retrieval phases. The results show the dependence of the non-linear correlations measures with the time of day and the type of the probe. In addition, the results indicate differences in the correlations measures with hippocampal regions between positive and lure probes. Besides confirming previous results on the influence of time-of-day on cognitive performance, the study demonstrates the effectiveness of the non-linear correlation analysis method for the characterization of fMRI task paradigms.
AB - Recent works shed light on the neural correlates of true and false recognition and the influence of time of day on cognitive performance. The current study aimed to investigate the modulation of the false memory formation by the time of day using a non-linear correlation analysis originally designed for fMRI resting-state data. Fifty-four young and healthy participants (32 females, mean age: 24.17 ± 3.56 y.o.) performed in MR scanner the modified Deese-Roediger-McDermott paradigm in short-term memory during one session in the morning and another in the evening. Subjects’ responses were modeled with a general linear model, which includes as a predictor the non-linear correlations of regional BOLD activity with the stimuli, separately for encoding and retrieval phases. The results show the dependence of the non-linear correlations measures with the time of day and the type of the probe. In addition, the results indicate differences in the correlations measures with hippocampal regions between positive and lure probes. Besides confirming previous results on the influence of time-of-day on cognitive performance, the study demonstrates the effectiveness of the non-linear correlation analysis method for the characterization of fMRI task paradigms.
KW - DRM paradigm
KW - fMRI
KW - functional dynamic connectivity
KW - memory distortions
KW - non-linear correlations
KW - point process analysis
KW - short-term (working) memory
UR - http://www.scopus.com/inward/record.url?scp=85121375164&partnerID=8YFLogxK
U2 - 10.3389/fnins.2021.778242
DO - 10.3389/fnins.2021.778242
M3 - Article
AN - SCOPUS:85121375164
SN - 1662-4548
VL - 15
JO - Frontiers in Neuroscience
JF - Frontiers in Neuroscience
M1 - 778242
ER -