TY - JOUR
T1 - Magnetic resonance imaging findings in pre-clinical Creutzfeldt-Jakob disease
AU - Álvarez, Francisco J.
AU - Bisbe, J.
AU - Bisbe, V.
AU - Dávalos, A.
PY - 2005/8
Y1 - 2005/8
N2 - The diagnosis of probable Creutzfeldt-Jakob disease (CJD) requires compatible clinical manifestations, typical electroencephalographical findings, and 14.3.3 protein positive in cerebrospinal fluid. Actually, MRI findings are not necessary, but they may support this diagnosis. The authors report a patient with definitive diagnosis of CJD who showed in a first MRI study performed two years before the clinical onset of the disease the same hyperintensities in caudate nuclei that were found in the last MRI. The authors think that these findings could be useful in detecting asymptomatic patients who need more extensive study and following.
AB - The diagnosis of probable Creutzfeldt-Jakob disease (CJD) requires compatible clinical manifestations, typical electroencephalographical findings, and 14.3.3 protein positive in cerebrospinal fluid. Actually, MRI findings are not necessary, but they may support this diagnosis. The authors report a patient with definitive diagnosis of CJD who showed in a first MRI study performed two years before the clinical onset of the disease the same hyperintensities in caudate nuclei that were found in the last MRI. The authors think that these findings could be useful in detecting asymptomatic patients who need more extensive study and following.
KW - Basal ganglia hyperintensities
KW - Creutzfeldt-Jakob disease
KW - Magnetic resonance imaging
UR - http://www.scopus.com/inward/record.url?scp=22244441150&partnerID=8YFLogxK
U2 - 10.1080/00207450590914491
DO - 10.1080/00207450590914491
M3 - Article
C2 - 16040363
AN - SCOPUS:22244441150
SN - 0020-7454
VL - 115
SP - 1219
EP - 1225
JO - International Journal of Neuroscience
JF - International Journal of Neuroscience
IS - 8
ER -