In times of war, religion features prominently in U.S. presidential rhetoric. It may be used to strengthen courage and hope or to serve as a powerful tool for accepting sacrifices and losses. In this article we examine the speeches of five presidents given specifically in periods of war: Lyndon B. Johnson, Richard M. Nixon, George H. W. Bush, George W. Bush, and Barack Obama. Then we analyze variations in the volume and type of religious content among these presidents; we use a textual content analysis methodology to study a representative sample of speeches given by the above-mentioned presidents in time of war. We conclude that U.S. presidents try to persuade the audience that the country is going to war to accomplish God’s will. Under this light, religious rhetoric appears to have a higher correlation with the enemy being fought than with the personal convictions of each president.