TY - JOUR
T1 - Impact of human immunodeficiency virus coinfection on the progression of mother-to-child transmitted hepatitis C virus infection
AU - Sánchez Ruiz, Emilia
AU - Claret-Teruel, Gemma
AU - Noguera-Julián, Antoni
AU - Muñoz-Almagro, Carmen
AU - Jiménez, Rafael
AU - Fortuny, Clàudia
N1 - Claret-Teruel G; Noguera-Julian A; Esteva C; Muñoz-Almagro C; Sánchez E; Jiménez R; Fortuny C
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Data on mother-to-child transmitted human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfection are scarce. A prospective observational study with a cohort of 70 HCV-infected children (13 of whom were HIV/HCV-coinfected; mean follow-up: 7.3 years) is presented. In our series, surrogate markers of disease progression (HCV viremia, maximum alanine aminotransferase values, and spontaneous HCV infection clearance) suggest that the evolution of liver disease in HIV/HCV-coinfected pediatric patients is more aggressive than it is in HCV-only infected children.
AB - Data on mother-to-child transmitted human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfection are scarce. A prospective observational study with a cohort of 70 HCV-infected children (13 of whom were HIV/HCV-coinfected; mean follow-up: 7.3 years) is presented. In our series, surrogate markers of disease progression (HCV viremia, maximum alanine aminotransferase values, and spontaneous HCV infection clearance) suggest that the evolution of liver disease in HIV/HCV-coinfected pediatric patients is more aggressive than it is in HCV-only infected children.
KW - Antiretrovil therapy
KW - Hepatitis C Virus
KW - Coinfection/epidemiology
KW - Human Immunodeficiency virus
KW - Mother-to-child transmission
UR - https://www.scopus.com/pages/publications/80051943538
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000294044400022
U2 - 10.1097/INF.0b013e3182196ab4
DO - 10.1097/INF.0b013e3182196ab4
M3 - Article
SN - 0891-3668
VL - 30
SP - 801
EP - 804
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 9
ER -
