Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery

P. Garg; S. Pandey; Hoon Seonwoo; Seungmin Yeom; Yun Hoon Choung; Chong Su Cho; Pill Hoon Choung; Jong Hoon Chung

doi:10.1039/c4cc09871d

Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery

P. Garg
, S. Pandey
, Hoon Seonwoo
, Seungmin Yeom
, Yun Hoon Choung
, Chong Su Cho
, Pill Hoon Choung^*
, Jong Hoon Chung

^*Autor corresponent d’aquest treball

Producció científica: Article en revista indexada › Article › Avaluat per experts

18 Cites (Scopus)

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Here, we introduce a polydixylitol based highly osmotic polymer that not only transmigrates the BBB by intra-arterial infusion of osmotic polyol but also triggers cellular uptake via modulation of caveolae mediated endocytosis.

Idioma original	Anglès
Pàgines (de-a)	3645-3648
Nombre de pàgines	4
Revista	Chemical Communications
Volum	51
Número	17
DOIs	https://doi.org/10.1039/c4cc09871d
Estat de la publicació	Publicada - 28 de febr. 2015
Publicat externament	Sí

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title = "Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery",

abstract = "Here, we introduce a polydixylitol based highly osmotic polymer that not only transmigrates the BBB by intra-arterial infusion of osmotic polyol but also triggers cellular uptake via modulation of caveolae mediated endocytosis.",

author = "P. Garg and S. Pandey and Hoon Seonwoo and Seungmin Yeom and Choung, \{Yun Hoon\} and Cho, \{Chong Su\} and Choung, \{Pill Hoon\} and \{Hoon Chung\}, Jong",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

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T1 - Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery

AU - Garg, P.

AU - Pandey, S.

AU - Seonwoo, Hoon

AU - Yeom, Seungmin

AU - Choung, Yun Hoon

AU - Cho, Chong Su

AU - Choung, Pill Hoon

AU - Hoon Chung, Jong

PY - 2015/2/28

Y1 - 2015/2/28

N2 - Here, we introduce a polydixylitol based highly osmotic polymer that not only transmigrates the BBB by intra-arterial infusion of osmotic polyol but also triggers cellular uptake via modulation of caveolae mediated endocytosis.

AB - Here, we introduce a polydixylitol based highly osmotic polymer that not only transmigrates the BBB by intra-arterial infusion of osmotic polyol but also triggers cellular uptake via modulation of caveolae mediated endocytosis.

UR - https://www.scopus.com/pages/publications/84923166783

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DO - 10.1039/c4cc09871d

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ER -

Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery

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