TY - JOUR
T1 - From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols
T2 - A view in perspective
AU - Medio-Simón, Mercedes
AU - Alemán, Pedro
AU - Cuenca, Ana
AU - Gil, Jesús
AU - Rodríguez, Nuria
AU - Asensio, Gregorio
PY - 2005/4/8
Y1 - 2005/4/8
N2 - A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.
AB - A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.
KW - Enantioselective protonation
KW - Enolates
KW - Sulfinyl alcohols
UR - http://www.scopus.com/inward/record.url?scp=20044386201&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000235707600024&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.3998/ark.5550190.0006.924
DO - 10.3998/ark.5550190.0006.924
M3 - Review
AN - SCOPUS:20044386201
SN - 1424-6376
VL - 2005
SP - 266
EP - 286
JO - Arkivoc
JF - Arkivoc
IS - 9
ER -