Resum
A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.
Idioma original | Anglès |
---|---|
Pàgines (de-a) | 266-286 |
Nombre de pàgines | 21 |
Revista | Arkivoc |
Volum | 2005 |
Número | 9 |
Estat de la publicació | Publicada - 8 d’abr. 2005 |
Publicat externament | Sí |