TY - JOUR
T1 - Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols
AU - Asensio, Gregorio
AU - Alemán, Pedro
AU - Cuenca, Ana
AU - Gil, Jesús
AU - Medio-Simón, Mercedes
PY - 1998/11/27
Y1 - 1998/11/27
N2 - The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.
AB - The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.
KW - Beta-hydroxy sulfoxides
KW - Enantioselective alkylation
KW - Cyclic-ketones
KW - Carbanions
KW - Reduction
UR - http://www.scopus.com/inward/record.url?scp=0032573446&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000077634600023&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1016/S0957-4166(98)00426-1
DO - 10.1016/S0957-4166(98)00426-1
M3 - Article
AN - SCOPUS:0032573446
SN - 0957-4166
VL - 9
SP - 4073
EP - 4078
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 22
ER -