Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols

Gregorio Asensio; Pedro Alemán; Ana Cuenca; Jesús Gil; Mercedes Medio-Simón

doi:10.1016/S0957-4166(98)00426-1

Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols

Gregorio Asensio^*, Pedro Alemán, Ana Cuenca, Jesús Gil, Mercedes Medio-Simón

^*Autor corresponent d’aquest treball

Producció científica: Article en revista indexada › Article › Avaluat per experts

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The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.

Idioma original	Anglès
Pàgines (de-a)	4073-4078
Nombre de pàgines	6
Revista	Tetrahedron Asymmetry
Volum	9
Número	22
DOIs	https://doi.org/10.1016/S0957-4166(98)00426-1
Estat de la publicació	Publicada - 27 de nov. 1998
Publicat externament	Sí

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title = "Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols",

abstract = "The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.",

keywords = "Beta-hydroxy sulfoxides, Enantioselective alkylation, Cyclic-ketones, Carbanions, Reduction",

author = "Gregorio Asensio and Pedro Alem{\'a}n and Ana Cuenca and Jes{\'u}s Gil and Mercedes Medio-Sim{\'o}n",

year = "1998",

month = nov,

day = "27",

doi = "10.1016/S0957-4166(98)00426-1",

language = "English",

volume = "9",

pages = "4073--4078",

journal = "Tetrahedron Asymmetry",

issn = "0957-4166",

publisher = "Elsevier Ltd.",

number = "22",

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TY - JOUR

T1 - Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols

AU - Asensio, Gregorio

AU - Alemán, Pedro

AU - Cuenca, Ana

AU - Gil, Jesús

AU - Medio-Simón, Mercedes

PY - 1998/11/27

Y1 - 1998/11/27

N2 - The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.

AB - The efficient asymmetric protonation of lithium enolates of 2- alkylcycloalkanones (87-96% ee) with readily accessible chiral α-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to -100°C.

KW - Beta-hydroxy sulfoxides

KW - Enantioselective alkylation

KW - Cyclic-ketones

KW - Carbanions

KW - Reduction

UR - http://www.scopus.com/inward/record.url?scp=0032573446&partnerID=8YFLogxK

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_univeritat_ramon_llull&SrcAuth=WosAPI&KeyUT=WOS:000077634600023&DestLinkType=FullRecord&DestApp=WOS

U2 - 10.1016/S0957-4166(98)00426-1

DO - 10.1016/S0957-4166(98)00426-1

M3 - Article

AN - SCOPUS:0032573446

SN - 0957-4166

VL - 9

SP - 4073

EP - 4078

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 22

ER -

Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols

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