Design, synthesis and biological activity of acyl substituted 3-amino-5-methyl-1,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones as potential hypnotic drugs

Pharmacology, Toxicology and Pharmaceutical Science

• Biological Activity 100%
• Hypnotic 100%
• Ligand 50%
• Receptor 50%
• 4 Aminobutyric Acid A Receptor 50%
• Zolpidem 50%
• ADME 50%
• Zaleplon 50%
• Nonbenzodiazepine 50%
• Indiplon 50%

Neuroscience

• Ligand 50%
• Eicosanoid Receptor 50%
• Selectivity 50%
• Nonbenzodiazepine 50%
• Zolpidem 50%
• GABAA Receptor 50%
• Zaleplon 50%