A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents

Oriol Planas; Thibault Gallavardin; Santi Nonell

doi:10.1039/c4cc09070e

A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents

Oriol Planas, Thibault Gallavardin, Santi Nonell

IQS School of Engineering

Producció científica: Article en revista indexada › Article › Avaluat per experts

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Resum

Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The conjugates show fluorescence in the near-infrared and are capable of photosensitizing the production of the cytotoxic species singlet oxygen.

Idioma original	Anglès
Pàgines (de-a)	5586-5589
Nombre de pàgines	4
Revista	Chemical Communications
Volum	51
Número	26
DOIs	https://doi.org/10.1039/c4cc09070e
Estat de la publicació	Publicada - 4 d’abr. 2015

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10.1039/c4cc09070e

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title = "A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents",

abstract = "Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The conjugates show fluorescence in the near-infrared and are capable of photosensitizing the production of the cytotoxic species singlet oxygen.",

author = "Oriol Planas and Thibault Gallavardin and Santi Nonell",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

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doi = "10.1039/c4cc09070e",

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T1 - A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents

AU - Planas, Oriol

AU - Gallavardin, Thibault

AU - Nonell, Santi

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015/4/4

Y1 - 2015/4/4

N2 - Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The conjugates show fluorescence in the near-infrared and are capable of photosensitizing the production of the cytotoxic species singlet oxygen.

AB - Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The conjugates show fluorescence in the near-infrared and are capable of photosensitizing the production of the cytotoxic species singlet oxygen.

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U2 - 10.1039/c4cc09070e

DO - 10.1039/c4cc09070e

M3 - Article

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AN - SCOPUS:84925321594

SN - 1359-7345

VL - 51

SP - 5586

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JO - Chemical Communications

JF - Chemical Communications

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ER -

A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents

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